Figure 6.

BBIQ enhances IgG antibody responses in influenza vaccinated mice. Female C57BL/6 mice, 6 to 8 week old, were immunized twice i.m. at a 2-week interval with recombinant hemagglutinin (rHA) protein 1μg alone or admixed with 10μg imiquimod or BBIQ in 50μl total volume. Blood samples were collected 2 weeks after the second immunization and antigen-specific IgG1 or IgG2c antibodies measured by ELISA with results shown as the OD (*p < .05, **p < .01).