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. 2020 Aug 21;10(23):10483–10497. doi: 10.7150/thno.45614

Figure 1.

Figure 1

IMQ-induced psoriasis-associated immune cell populations in WT and Vsir-/- psoriatic mice were identified. (A)Schematic diagram of the experimental design. (B) Profiles of the tSNE plots of 23,258 cells extracted from back skin of WT (12,040 cells) and Vsir-/- (11,218 cells) psoriatic mice with each cell colour-coded according to sample origin (left panel) and associated cell type (right panel). (C) For each of 12 cell clusters (from left to right), the fraction of cells originating from WT and Vsir-/- psoriatic mice; the number of cells and box plots of the number of transcripts are shown to provide an overview of all immune cells. IMQ, imiquimod. NK cells, natural killer cells. tSNE, t-distributed stochastic neighbour embedding. UMI, unique molecular identifier. Vsir-/-, Vsir knockout mice. WT, wild type.