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18F-HX4 microPET establishes in vivo proof-of-principle. A) Reconstruction of representative PET images two hours after tracer injection in HCT116 and H1299 xenografts. Tumours are delineated using a white line. Uptake of 18F-HX4 is higher in NfsA_Ec expressing tumours in comparison to WT. B) Quantification of tumour:blood ratios of the different experimental groups.
