Table 3.
Geometric means of hSBA titers at baseline (Day 0) and Day 30.
| MenACYW-TT (N = 384) |
MCV4-DT (N = 389) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Serogroup | Time Point | M | GMT | (95% CI) | M | GMT | (95% CI) | GMTR |
| A | Day 0 | 384 | 13.7 | (12.2, 15.5) | 389 | 15.1 | (13.5, 16.9) | |
| Day 30 | 384 | 497 | (436, 568) | 389 | 296 | (256, 343) | 1.68 | |
| C | Day 0 | 384 | 11.0 | (9.32, 13.1) | 389 | 10.6 | (9.10, 12.4) | |
| Day 30 | 384 | 2618 | (2227, 3078) | 389 | 599 | (504, 711) | 4.37 | |
| W | Day 0 | 384 | 9.76 | (8.46, 11.2) | 389 | 10.6 | (9.21, 12.2) | |
| Day 30 | 384 | 1747 | (1508, 2025) | 389 | 723 | (614, 853) | 2.42 | |
| Y | Day 0 | 384 | 7.70 | (6.56, 9.04) | 389 | 7.27 | (6.21, 8.50) | |
| Day 30 | 384 | 2070 | (1807, 2371) | 389 | 811 | (699, 941) | 2.55 | |
CI, confidence interval; GMT, geometric mean titer; GMTR, geometric mean titer ratio (MenACYW-TT/MCV4-DT); hSBA, human complement serum bactericidal antibody assay; M, number of subjects with valid serology results for the particular serogroup and time point; N, number of participants in the per-protocol analysis set.