Table 1.
Average number of hospitalization across different vaccination period (pre-PCV, early vaccination using PCV7, and routine vaccination using PCV13), disaggregated into different age groups.
| Period | Pre-PCV 1998-2003 |
Early 2005-2009 |
Routine 2011-2015 |
% change* | p value** |
|---|---|---|---|---|---|
| All-cause pneumonia | |||||
| POPULATION | 5639 | 5937 | 7834 | +32.0% | *** |
| < 5 | 596 | 596 | 373 | −37.4% | *** |
| 5-14 | 193 | 206 | 152 | −26.2% | 0.061 |
| 15-24 | 110 | 81 | 53 | −34.6% | 0.061 |
| 24-44 | 398 | 422 | 368 | −12.8% | 0.095 |
| 45-64 | 817 | 875 | 1048 | +19.8% | *** |
| > 64 | 3525 | 3759 | 5840 | +55.4% | *** |
| Pneumococcal pneumonia | |||||
| POPULATION | 1734 | 1594 | 671 | −57.9% | *** |
| < 5 | 222 | 130 | 23 | −82.3% | *** |
| 5-14 | 63 | 48 | 12 | −75.0% | *** |
| 15-24 | 27 | 22 | 6 | −72.7% | *** |
| 24-44 | 112 | 114 | 43 | −43.0% | *** |
| 45-64 | 220 | 228 | 112 | −50.9% | *** |
| > 64 | 1090 | 1051 | 476 | −54.7 | *** |
| Pneumococcal invasive diseases | |||||
| POPULATION | 1778 | 1666 | 741 | −55.5% | **** |
| < 5 | 227 | 137 | 25 | −81.8% | *** |
| 5-14 | 65 | 49 | 13 | −73.5% | *** |
| 15-24 | 28 | 24 | 6 | −75.0% | *** |
| 24-44 | 118 | 124 | 51 | −73.0% | *** |
| 45-64 | 230 | 245 | 130 | −46.9% | *** |
| > 64 | 1110 | 1086 | 515 | −52.5% | *** |
*% change comparing private market use and routine immunization.
**p-value according to one-way ANOVA
***p < 0.0001