Table 1.

Study details.

Article	First author	Kind of mouthrinse	Antiseptic/Antibacterial	Placebo	Contaminate	Reduction in viral load	Testing time	Author`s Conclusions
In vitro Virucidal Effectiveness of a 0.12%-Chlorhexidine Gluconate Mouthrinse 6 November 1989	D BERNSTEIN [1]	Peridex (Chlorhexidine Gluconate 0.12% Oral Rinse)	Antimicrobial	Excipients	Herpes Simplex Cytomegalovirus Influenza A Parainfluenza Hepatitis polio virus	Reductions in all virus concentration except the polio virus.	30 s-5 m-15 m	Virucidal effectiveness of 0.12%-Chlorhexidine Gluconate increased with time.
In vitro effect of oral antiseptics on human immunodeficiency virus-1 and herpes simplex virus type1 Baqui Jul,2001	AAMA Baqui [2]	-ListerineA Antiseptic (LA) -Tartar control ListerineA Antiseptic (TLA) -PeridexA (PX, 0.12% chlorhexidine digluconate) -Chlorhexidine digluconate (CHX, 20% w/v)	Antimicrobial	–	Human Immunodeficiency Virus (HIV-1) Herpes simplex virus (HSV-1)	Reduced viral load.	30 sec	Each of the mouthrinses tested possess in vitro anti-HIV and anti-HSV properties at their commercial concentrations and some demonstrated efficacy up to 1:16 dilutions.
In Vitro Virucidal Effect of Mouthrinse Containing C31 G on Seasonal Influenza Viruses Lee 1 April 2014	Dong-Hun Lee [3]	−3.0% solution of C31 G - mouthrinse containing 3.0% C31 G, SenseTime (ILDONG Pharmaceutical, Korea),	Antimicrobial	Phosphate buffered saline (PBS)	B/Brisbane/60/2008, virus A/Brisbane/59/2007 (H1N1) A/Brisbane/10/2007 (H3N2)	Reduced and inhibited the infection of seasonal influenza viruses.	30 min	C31 G and Sense-Time completely inactivated all of the tested viruses Although Sense-Time contained the same concentration of C31 G, the C31 G solution showed a higher virucidal.
Rapid and Effective Virucidal Activity of PovidoneIodine Products Against Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and Modified Vaccinia Virus Ankara (MVA) Eggers 28 September 2015	Maren Eggers [4]	1% PVP-I	Antiseptic	Double-distilled water	MERS-CoV	Reduction of viral load required 30 s of exposure at the 1:10 dilution	15s, 30s, 60 s	the excellent virucidal activity of PVP-I against enveloped viruses.
In Vitro Bactericidal and Virucidal Efficacy of Povidone-Iodine Gargle/Mouthwash Against Respiratory and Oral Tract Pathogens Eggers 9 April 2018	Maren Eggers [5]	7% PVP-I	Antiseptic	Distilled water	SARS-CoV MERS-CoV influenza virus A subtype H1N1 rotavirus	All viral titres were reduced by between 4.40 and 6.00 log10 TCID50/ml.	Clean conditions: 15s- 30s- 60s- 120s Dirty conditions: 15s- 30s	All viral titres were reduced after 15 s of contact time with PVP-I gargle at a concentration of 0.7% and 0.23%