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. 2020 Sep 10;15(9):e0238594. doi: 10.1371/journal.pone.0238594

Fig 5. Gene expression signatures identified in BRC12 and BRC13 tumor cell subpopulations.

Fig 5

A hypoxia gene signature composed of 3 published signatures [30–32] was found in BRC12 CD184lo and BRC13 CD49flo subpopulations (a) while a proliferative gene signature identified in histologically normal breast tissue from cancer patients [41] was present in BRC12 CD184hi and BRC13 CD133hi subpopulations (b). Genes with lowest FDR and highest x-fold values are labeled in volcano plots and marked with arrows in heatmaps, respectively.