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. 2020 Jul 1;54(5):378–386. doi: 10.4132/jptm.2020.06.01

Table 3.

The sensitivity, specificity, and accuracy of p53 immunohistochemistry for predicting TP53 mutation, cut-off 10%

TP53 mutation Sensitivity (%) Specificity (%) Accuracy (%)
Nonsynonymous mutation by p53 strong expression 90.9 95.4 94.2
Other type mutation by negative expression of p53 79.0 88.1 86.7
Wild-type by weak expression of p53 80.9 92.3 85.8