Table 1.
Summary of information on cases of clinically suspected cardiac sarcoidosis
| Case No.a | Sex | Ageb | Extracardiac sarcoidosis | Steroid | Cardiac rhythm | Heart blockc | Ventricular arrhythmiad | LVEF (%) | Heart TPL | MRI diagnosis |
|---|---|---|---|---|---|---|---|---|---|---|
| Group 1 | ||||||||||
| 1-1 | M | > 40 | No | No | Sinus | No | No | 22 | Yes | Probable |
| 1-2 | M | > 40 | No | No | Sinus | No | No | 33 | Yes | Probable |
| 1-3 | F | > 50 | Not definite | No | Sinus | No | No | 51 | No | Probable |
| 1-4 | M | > 60 | No | Unknown | Paroxysmal AF | No | No | 30 | No | × |
| 1-5 | F | > 60 | No | No | Sinus | No | No | 42 | No | Probable |
| Group 2 | ||||||||||
| 2-1 | F | > 70 | No | No | AF | No | No | 15 | No | Probable |
| 2-2 | F | > 70 | No | No | AF | No | No | 15 | No | Probable |
| Group 3 | ||||||||||
| 3-1 | M | > 50 | No | No | Sinus | Yes | Yes | 44 | No | Probable |
| 3-2 | F | > 70 | No | Yes | Paroxysmal AF | Yes | No | 40 | No | Possible |
| 3-3 | M | > 40 | No | No | Sinus | Yes | Yes | 36 | Yes | Nonspecific |
| 3-4 | F | > 90 | No | Unknown | Sinus | Yes | Yes | 30 | No | Probable |
| 3-5 | F | > 50 | Yes (lung, lymph node) | Unknown | Sinus | Yes | Yes | 50 | No | × |
| 3-6 | F | > 70 | No | Yes | Sinus | No | No | 22 | No | Probable |
| Group 4 | ||||||||||
| 4-1 | M | > 60 | No | Unknown | Sinus | No | Yes | 30 | Yes | Probable |
| 4-2 | M | > 40 | No | No | Sinus | No | No | 33 | Yes | Probable |
| 4-3 | M | > 70 | No | Unknown | AF | No | No | 56 | No | Nonspecific |
| Group 5 | ||||||||||
| 5-1 | M | > 70 | No | No | Sinus | No | No | 48 | No | Probable |
| 5-2 | F | > 60 | No | Yes | Sinus | No | No | 35 | No | Nonspecific |
| 5-3 | F | > 70 | No | Yes | Paroxysmal AF | No | Yes | 35 | No | Nonspecific |
| 5-4 | M | > 60 | No | No | Sinus | No | No | 48 | No | Nonspecific |
| 5-5 | M | > 70 | Yes (lymph node) | No | Sinus | No | Yes | 42 | No | Unlikely |
| 5-6 | F | > 50 | Yes (skin) | Yes | Sinus | Yes | No | 61 | No | Unlikely |
| Group 6 | ||||||||||
| 6-1 | M | > 50 | No | Unknown | Sinus | Yes | Yes | 46 | No | × |
| 6-2 | M | > 30 | No | No | Sinus | No | No | 30 | No | Nonspecific |
| 6-3 | M | > 20 | Yes (lymph node) | Yes | Sinus | No | No | 25 | No | Nonspecific |
| 6-4 | M | > 60 | No | Unknown | Sinus | No | No | 28 | No | Nonspecific |
| 6-5 | M | > 10 | No | Unknown | Sinus | No | No | 54 | No | Unlikely |
Group 1, endomyocardial biopsies with micro-granuloma as well as histiocytic infiltration, confluent fibrosis and fatty change; Group 2, endomyocardial biopsies with histiocytic infiltration, confluent fibrosis and fatty change but without micro-granuloma; Group 3, endomyocardial biopsies with confluent fibrosis associated with fatty tissue infiltration; Group 4, presence of confluent fibrosis without associated fatty tissue; Group 5, presence of fatty tissue without associated fibrosis; Group 6, none of four possible indicators on endomyocardial biopsy.
LVEF, left ventricular ejection fraction; TPL, transplantation; MRI, magnetic resonance imaging; M, male; F, female; AF, atrail fibrillation.
Cases 1-2 and 4-2 are a same case, cases 2-1 and 2-2 are another same case;
Age is expressed in 10-year interval;
Second degree Mobitz type II or thirddegree atrioventricular block;
Sustained ventricular tachycardia or ventricular fibrillation.