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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Curr Opin Cell Biol. 2020 Mar 3;65:150–155. doi: 10.1016/j.ceb.2020.01.009

Fig. 1. Membrane trafficking pathways controlled by endocytic regulatory proteins.

Fig. 1.

Endocytic trafficking traditionally includes the internalization of receptors and lipids from the plasma membrane, the fusion of internalized vesicles with the sorting endosome, recycling to the plasma membrane (often through a transitory compartment known as the Endocytic Recycling Compartment or ERC), transport to the lysosome, and trafficking to and from the Golgi apparatus in anterograde and retrograde transport (blue arrows). Somewhat surprisingly, recent studies have also demonstrated roles for vesicular transport and endocytic trafficking at mitochondria, peroxisomes and the centrosome (red arrows).