Table 3.
Autoallergen | Core Sequence | Epitope Count IEDB | Epitope Count NetMHCIIpan | HLA-DRB1 Alleles (IEDB and NetMHCIIpan overlap) |
---|---|---|---|---|
Horn s 1 | FRQLSHRFH | 28 | 63 | 15:03, 12:02, 11:04, 11:01, 08:04, 03:02,01:02 |
IRAKLRLQA | 38 | 60 | 15:03, 13:01, 12:02, 12:01, 11:04, 11:01, 08:04, 07:01, 03:02, 03:01,01:02 | |
Horn s 2 | IRKSKNILF | 127 | 110 | All alleles except 01:01 |
Horn s 3 | FKWVPVTDS | 34 | 24 | 08:02, 04:07, 04:05, 04:04, 04:01 |
MAAIEKVRK | 36 | 21 | 12:02, 11:04, 11:01, 08:04, 08:03, 08:02, 03:02, 03:01 | |
Horn s 4 | FRYFATLKV | 106 | 138 | All alleles except 13:02 |