Table 1.
Individuals carrying variants in autism-associated genes with comorbid ID.
| Autism- associated genes | Cases with ID | Autism cases (with or without ID) | Autism cases with comorbid ID | Autism cases without ID |
|---|---|---|---|---|
| ADNP | 134/134 | 114/134 | 114/114 | 0/114 |
| ANK2 | 1/1 | 1/1 | 1/1 | 0/1 |
| ANKRD11 | 10/10 | 9/10 | 9/9 | 0/9 |
| ARID1B | 137/153 | 80/153 | 80/80 | 0/80 |
| ASH1L | 14/14 | 4/14 | 4/4 | 0/4 |
| ASXL3 | 18/19 | 16/19 | 15/16 | 1/16 |
| BCL11A | 11/16 | 4/16 | 3/4 | 1/4 |
| CHD2 | 3/3 | 3/3 | 3/3 | 0/3 |
| CHD8 | 56/75 | 61/75 | 46/61 | 15/61 |
| CUL3 | 1/1 | 1/1 | 1/1 | 0/1 |
| DDX3X | 97/97 | 33/97 | 33/33 | 0/33 |
| DYRK1A | 7/26 | 9/26 | 7/9 | 2/9 |
| KMT2A | 76/99 | 12/99 | 10/12 | 2/12 |
| MECP2 | 1/1 | 1/1 | 1/1 | 0/1 |
| MYT1L | 1/1 | 1/1 | 1/1 | 0/1 |
| NRXN1 | 45/60 | 34/60 | 23/34 | 11/34 |
| POGZ | 48/49 | 29/49 | 29/29 | 0/29 |
| SCN2A | 19/33 | 9/33 | 7/9 | 2/9 |
| SETD5 | 15/16 | 7/16 | 7/7 | 0/7 |
| SHANK3 | 35/37 | 26/37 | 24/26 | 2/26 |
| SYNGAP1 | 11/23 | 11/23 | 11/11 | 0/11 |
| TCF20 | 47/48 | 32/48 | 31/32 | 1/32 |
| Total | 787/916 (85.9%) | 497/916 (54.3%) | 460/497 (92.6%) | 37/497 (7.4%) |