. Author manuscript; available in PMC: 2020 Sep 21.

Published in final edited form as: Lab Invest. 2020 Mar 6;100(10):1356–1366. doi: 10.1038/s41374-020-0413-8

Table 2.

Univariate Cox regression and C-indices using PS as a continuous variable.

Study	Sample Size^a	PS only			PS + Clin. variables
Study	Sample Size^a	P-val	HR	C-index	P-val	HR	C-index
TCGA	289	6.6E-12	0.92	0.66	1.5E-8	0.93	0.68
GSE9891	278	4.2E-9	0.97	0.7	4.6E-8	0.97	0.74
GSE32063	260	2.1E-3	0.88	0.6	0.01	0.9	0.64
GSE26712	185	1.1E-3	0.98	0.61	0.03	0.99	0.66
E.MTAB.386	129	2.3E-3	0.97	0.6	2.5E-3	0.96	0.63
PMID17290060	117	4.7E-4	0.97	0.66	7.4E-4	0.97	0.67
GSE17260	110	0.05	0.99	0.6	0.09	0.99	0.66

Sample size indicates number of gene expression samples used in analysis. PS = prognostic score. HR = hazard ratio. C-index = concordance index. Clin. variables include all clinical variables (stage, grade, age and/or debulking) available for each dataset (See Supp. Table 5).