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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Contraception. 2020 May 12;102(3):180–185. doi: 10.1016/j.contraception.2020.05.002

Table 4:

Final associations between patient characteristics and genetic variants and objective weight change in a study of etonogestrel implant users

Variable β 95% CI p-value
BMI (at enrollment)† 0.54 0.39, 0.70 9.39 x 10−12
CYP2C19 rs7088784 carrier −3.74 −6.12, −1.35 0.002
ESR1 rs9340799 homozygous variant† 14.10 6.86, 21.35 1.36 x 10−4

Performed using generalized linear modeling with a backward-stepwise approach

†

Statistically significant using Bonferroni corrected p-value cut-off < 5.0 x 10−4