Extended Data Fig. 1. Joint m⁶A peak calling and QTL mapping.

a, Distribution of merged m⁶A peak length. Dash line marks the mean peak width. b, Distribution of all m⁶A peaks vs. ePeaks on a meta-gene. c, Proportion of all m⁶A peaks vs. ePeaks in each genomic annotation. d, m⁶A motif learned by Homer2, and visualized using EDlogo package. e, Spatial distribution of m⁶A-QTLs illustrated by density plot of SNP to peak distances of m⁶A-QTL with nominal P-value < 1X10⁻⁴ in a 2 Mb window surrounding m⁶A peaks. We also showed the significance by the -log₁₀ P-value of the association tests in the blue dots. f, Volcano plot of overall statistics of m⁶A-QTLs with peak-level FDR < 10% (ePeaks). g, Distribution of the number of causal effects of ePeaks (FDR < 10%) by SuSiE fine-mapping with uniform prior. We set SuSiE parameters L = 3 (assuming at most three causal effects) and coverage = 0.95 (95% coverage for credible sets).