Experimental design is depicted in Figure 1A. Animals were bled via tail artery one week before the initiation of the drinking paradigm (basal) and 24 hours after the final drinking session. No changes were observed in platelet count before and after 8 weeks of IA20%2BC. n=8 Late Onset, n=8 Rapid Onset. Two-way repeated measures ANOVA; effect of drinking profile: F1,14=0.1841, p=0.6744; effect of time F1,14=0.1459, p=0.7083; interaction: F1,14=0.3293, p=0.5752.