Table 1.
Participant characteristics in a dose-finding study of contraceptive vaginal ring releasing estradiol 75 mcg, 100 mcg, or 200 mcg per day and segesterone acetate 200 mcg per day
| E2 75 mcg/day and SA 200 mcg/day n=22 |
E2 100 mcg/day and SA 200 mcg/day n=21 |
E2 200 mcg/day and SA 200 mcg/day n=22 |
|
|---|---|---|---|
| Age (years) | 27.0 ± 5.4 | 27.8 ± 6.6 | 30.0 ± 5.4 |
| Non-Hispanic ethnicity | 19 (86.4) | 20 (95.2) | 21 (95.5) |
| Race | |||
| White | 13 (59.1) | 14 (66.7) | 15 (68.2) |
| Black | 6 (27.3) | 3 (14.3) | 5 (22.7) |
| Other | 3 (13.6) | 4 (19.0) | 2 (9.1) |
| Gravidity | |||
| 0 | 14 (66.7) | 11 (52.4) | 13 (59.1) |
| 1 | 3 (14.3) | 2 (9.5) | 4 (18.2) |
| 2 or more | 4 (18.2) | 8 (38.1) | 5 (22.7) |
| Parity | |||
| 0 | 16 (72.7) | 13 (61.9) | 17 (77.3) |
| 1 | 1 (4.5) | 2 (10.0) | 2 (9.1) |
| 2 or more | 4 (18.2) | 6 (28.6) | 3 (13.6) |
| Weight (kg) | 71.2 ± 13.6 | 67.4 ± 12.7 | 70.8 ± 15.1 |
| Body Mass Index (kg/m2) | 25.9 ± 4.2 | 25.3 ± 4.5 | 25.8 ± 4.8 |
| <18.5 | 0 | 2 (9.5) | 1 (4.5) |
| 18.5 – <25.0 | 10 (45.5) | 9 (42.9) | 12 (54.5) |
| 25.0 – <30.0 | 6 (27.3) | 5 (23.8) | 4 (18.2) |
| ≥30.0 | 6 (27.3) | 5 (23.8) | 5 (22.7) |
| Current tobacco use | 0 | 2 (9.5) | 0 |
Data presented as mean ± standard deviation or n (%)
E2 = estradiol; SA = Segesterone Acetate