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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Obesity (Silver Spring). 2020 Aug 10;28(9):1631–1636. doi: 10.1002/oby.22929

Figure 1. High-dose vitamin A supplementation improves retinol levels in tissues of obese mice.

Figure 1.

Mice received 600 IU vitamin A or PBS orally on d.0,3,7,21, 24 and 28. Retinol levels were evaluated in the (A) liver, (B) lung, (C) adipose tissue and (D) of lean and diet-induced obese (DIO) mice one week after administration of last vitamin A dose (d.35). Each dot represents a single mouse with 5 mice per group. A representative experiment is shown for two independent experiments, each with 5 mice per group. Significant differences were determined by two-way ANOVA followed by Tukey’s multiple comparisons test. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001.