Table 1.

Weight-based dosing of thromboprophylaxis for acutely ill medical patients at high VTE risk (without bleeding risk factors)

Weight, kg	No renal impairment; eGFR ≥30 mL/min	Renal impairment; eGFR 15-30 mL/min	End-stage renal impairment; eGFR <15 mL/min or dialysis dependent
<50	Enoxaparin: 20 mg daily	Contact hematology for advice	Unfractionated heparin: 5000 U bd
50-100	Enoxaparin: 40 mg daily	Enoxaparin: 20 mg daily	Unfractionated heparin: 5000 U bd
101-150	Enoxaparin: 40 mg bd or 80 mg daily	Enoxaparin: 20 mg daily	Unfractionated heparin: 5000 U tds
>150	Enoxaparin: 60 mg bd or 120 mg daily	Contact hematology for advice	Unfractionated heparin: 5000 U tds

bd, twice daily; eGFR, estimated glomerular filtration rate; tds, 3 times daily.