Fig. 4. Matching of expression patterns of NogginA (a–j) and NogginC (k–t).

a At stage 25 NogginA is expressed in somites, especially in dorsal and ventral angles, notochord, hypochord, neural tube. b, c Transverse sections, the section levels are shown in (a). d Whole mount expression of NogginA at stage 27. e–g Saggital section of embryo of stage 27 reveals the expression of NogginA at the border of telencephalon and diencephalon along anterior intraencephalic sulcus, in zona limitans intrathalamica and at mid-hind brain boundary and in the eyes. h–j In the tailbud the expression of NogginA increases in the notochord of the growing tail. The levels of transverse sections are shown in (h). k–m At stage 25 NogginC is expressed in somites, notochord, neural tube and premigratory neural crest cells. l, m Transverse sections, the section levels are shown in (k). n Whole mount expression of NogginC at stage27. o–q Saggital sections reveal the stronger expression in the ventral part of the telencephalon and weak expression in ZLI and in otic cups. r–t at stage 27 NogginC is expressed in somites, notochord, neural tube at the trunk level (s), but in the growing tail (t) it reveals at a high level in the central (ventricular) zone of the neural tube. The levels of transverse sections are shown in (r). For abbreviations see Fig. 3.