Table 1.
Characteristics | Natural cycles (n = 513) | HRT cycles (n = 287) | P-value |
---|---|---|---|
Age (years) | 28.74 ± 2.89 | 29.08 ± 3.01 | 0.117 |
Body-mass index (kg/m) | 22.32 ± 3.07 | 22.52 ± 3.30 | 0.379 |
Duration of infertility (years) | 3.26 ± 2.11 | 3.29 ± 2.35 | 0.846 |
Previous conception n (%) | 219/513 (42.69) | 133/287 (46.34) | 0.318 |
Indications for IVF | 0.364 | ||
Tubal factor | 276/513 (53.80) | 156/287 (54.36) | |
Male factor | 113/513 (22.03) | 64/287 (22.30) | |
Unexplained infertility | 20/513 (3.90) | 18/287 (6.27) | |
Combined factors | 104/513 (20.27) | 49/287 (17.07) | |
Antral follicle count in both ovaries | 16.46 ± 5.46 | 16.87 ± 5.99 | 0.339 |
Baseline sex hormone | |||
FSH (IU/L) | 6.34 ± 1.50 | 6.32 ± 1.46 | 0.812 |
LH (IU/L) | 4.78 ± 1.93 | 4.83 ± 2.21 | 0.717 |
Oestradiol (pg/mL) | 37.07 ± 14.60 | 37.94 ± 15.64 | 0.430 |
Total testosterone (ng/dL) | 28.46 ± 14.03 | 35.96 ± 17.82 | <0.001 |
Fresh cycle variables | |||
Days of ovarian stimulation | 9.28 ± 1.40 | 9.49 ± 1.68 | 0.056 |
Total gonadotropin dose (IU) | 1559.32 ± 479.52 | 1634.78 ± 500.26 | 0.036 |
Oestradial level on HCG trigger day (pmol/L) | 3431.55 ± 1810.08 | 3758.37 ± 1801.59 | 0.020 |
Progesterone level on HCG trigger day (nmol/L) | 1.14 ± 0.52 | 1.26 ± 0.58 | 0.006 |
Endometrial thickness on HCG trigger day (cm) | 1.07 ± 0.20 | 1.06 ± 0.20 | 0.512 |
No. of oocytes retrieved | 14.29 ± 5.74 | 14.69 ± 5.68 | 0.339 |
No. of 2PN embryos | 9.43 ± 3.97 | 10.17 ± 4.53 | 0.015 |
No. of cleavage embryos | 9.29 ± 3.96 | 9.94 ± 4.36 | 0.032 |
Fertilization method | 0.333 | ||
IVF n (%) | 359/513 (69.98) | 210/287 (73.17) | |
ICSI n (%) | 127/513 (24.76) | 68/287 (23.69) | |
IVF +ICSI n (%) | 27/513 (5.26) | 9/287 (3.14) | |
No. of day-3 embryos suitable for transfer | 6.96 ± 2.99 | 7.59 ± 3.69 | 0.015 |
OHSS n (%) | 3/513 (0.58) | 4/287 (1.39) | 0.258 |
FET cycle variables | |||
Endometrial thickness before transfer (cm) | 1.00 ± 0.17 | 0.94 ± 0.16 | <0.001 |
Timing of embryo transfer—no./total no. (%) | 0.853 | ||
Day 5 | 465/513 (90.64) | 259/287 (90.24) | |
Day 6 | 48/513 (9.36) | 28/287 (9.76) | |
No. of remaining frozen blastocysts | 4.19 ± 2.90 | 4.27 ± 3.00 | 0.720 |