Table 4.

Logistic regression for the effect of natural cycle vs. HRT cycle regimen on obstetric complication.

			Model 1		Model 2
	Unadjusted OR (95% CI)	P-value	Adjusted OR (95% CI)	P value	Adjusted OR (95% CI)	P-value
Total live birth	1.456 (1.089–1.948)	0.011	1.411 (1.011–1.970)	0.043	1.366 (0.975–1.913)	0.070
Clinical pregnancy	1.499 (1.111–2.023)	0.008	1.444 (1.022–2.041)	0.037*	1.406 (0.992–1.991)	0.055
Ongoing pregnancy	1.481 (1.105–1.984)	0.008	1.443 (1.031–2.020)	0.033	1.387 (0.988–1.948)	0.059
Biochemical miscarriage	0.331 (0.195–0.564)	<0.001	0.323 (0.174–0.599)	<0.001*	0.328 (0.176–0.611)	<0.001
Gestational diabetes	1.019 (0.570–1.819)	0.950	0.850 (0.428–1.688)	0.642	0.886 (0.446–1.762)	0.730
Gestational hypertension	0.767 (0.247–2.382)	0.765	0.652 (0.186–2.289)	0.505	0.662 (0.187–2.348)	0.523
Pre-eclampsia	0.717 (0.251–2.048)	0.580	0.732 (0.238–2.250)	0.586	0.749 (0.244–2.300)	0.613
Preterm delivery	1.066 (0.493–2.306)	0.870	1.273 (0.518–3.130)	0.599	1.274 (0.520–3.124)	0.596
Small for gestational age	0.729 (0.322–1.649)	0.447	0.712 (0.293–1.728)	0.452	0.700 (0.285–1.715)	0.435
Large for gestational age	0.997 (0.601–1.655)	0.992	1.064 (0.602–1.881)	0.832	1.084 (0.613–1.916)	0.782

Modal 1 is adjusted for total testosterone, total gonadotropin dose (IU), oestradial level on HCG trigger day (pmol/L), progesterone level on HCG trigger day (nmol/L), No. of 2PN embryos, No. of cleavage embryos, No. of day-3 embryos suitable for transfer and endometrial thickness before transfer (cm). Modal 2 is adjusted for age, FSH, total testosterone, total gonadotropin dose (IU), oestradial level on HCG trigger day (pmol/L), progesterone level on HCG trigger day (nmol/L), No. of 2PN embryos, No. of cleavage embryos, No. of day-3 embryos suitable for transfer and endometrial thickness before transfer (cm). HRT cycle regimen was set to be the referent group.

^*Value of Hosmer-Lemeshow Test goodness-of-fit <0.05.