TABLE 1.
Differentially expressed proteins in chronically pesticide-exposed patients. Volcano plot data.
| Accession (UniProt) | Description | −Log2 fold difference | −Log p-value |
| Down regulated proteins in exposed samples | |||
| Q15848 | Adiponectin OS = Homo sapiens OX = 9606 GN = ADIPOQ PE = 1 SV = 1 | −0,577652 | 0,877936 |
| P02652 | Apolipoprotein A-II OS = Homo sapiens OX = 9606 GN = APOA2 PE = 1 SV = 1 | −1,29743 | 2,95751 |
| P15169 | Carboxypeptidase N catalytic chain OS = Homo sapiens OX = 9606 GN = CPN1 PE = 1 SV = 1 | −0,5372 | 0,903306 |
| P12259 | Coagulation factor V OS = Homo sapiens OX = 9606 GN = F5 PE = 1 SV = 4 | −2,18176 | 0,848073 |
| A0A0B4J1Y9 | Immunoglobulin heavy variable 3-72 OS = Homo sapiens OX = 9606 GN = IGHV3-72 PE = 3 SV = 1 | −0,937188 | 0,972346 |
| A0A0A0MT36 | Immunoglobulin kappa variable 6D-21 OS = Homo sapiens OX = 9606 GN = IGKV6D-21 PE = 3 SV = 1 | −2,69985 | 0,985784 |
| P01721 | Immunoglobulin lambda variable 6-57 OS = Homo sapiens OX = 9606 GN = IGLV6-57 PE = 1 SV = 2 | −2,4305 | 0,645198 |
| P18428 | Lipopolysaccharide-binding protein OS = Homo sapiens OX = 9606 GN = LBP PE = 1 SV = 3 | −0,877242 | 0,632545 |
| Up regulated proteins in exposed samples | |||
| P02763 | Alpha-1-acid glycoprotein 1 OS = Homo sapiens OX = 9606 GN = ORM1 PE = 1 SV = 1 | 0,282142 | 0,549393 |
| P19652 | Alpha-1-acid glycoprotein 2 OS = Homo sapiens OX = 9606 GN = ORM2 PE = 1 SV = 2 | 0,672468 | 0,780538 |
| P01019 | Angiotensinogen OS = Homo sapiens OX = 9606 GN = AGT PE = 1 SV = 1 | 0,598796 | 0,51995 |
| P06727 | Apolipoprotein A-IV OS = Homo sapiens OX = 9606 GN = APOA4 PE = 1 SV = 3 | 0,811802 | 0,619374 |
| P02655 | Apolipoprotein C-II OS = Homo sapiens OX = 9606 GN = APOC2 PE = 1 SV = 1 | 0,237511 | 0,792502 |
| P02749 | Beta-2-glycoprotein 1 OS = Homo sapiens OX = 9606 GN = APOH PE = 1 SV = 3 | 1,20994 | 0,951809 |
| P04003 | C4b-binding protein alpha chain OS = Homo sapiens OX = 9606 GN = C4BPA PE = 1 SV = 2 | 0,446286 | 0,52209 |
| P00915 | Carbonic anhydrase 1 OS = Homo sapiens OX = 9606 GN = CA1 PE = 1 SV = 2 | 1,67218 | 1,19446 |
| P00918 | Carbonic anhydrase 2 OS = Homo sapiens OX = 9606 GN = CA2 PE = 1 SV = 2 | 0,632465 | 1,43293 |
| P22792 | Carboxypeptidase N subunit 2 OS = Homo sapiens OX = 9606 GN = CPN2 PE = 1 SV = 3 | 1,25728 | 1,98658 |
| P04040 | Catalase OS = Homo sapiens OX = 9606 GN = CAT PE = 1 SV = 3 | 0,913062 | 1,51147 |
| O43866 | CD5 antigen-like OS = Homo sapiens OX = 9606 GN = CD5L PE = 1 SV = 1 | 0,583446 | 0,511082 |
| P02745 | Complement C1q subcomponent subunit A OS = Homo sapiens OX = 9606 GN = C1QA PE = 1 SV = 2 | 0,816096 | 1,05262 |
| P02747 | Complement C1q subcomponent subunit C OS = Homo sapiens OX = 9606 GN = C1QC PE = 1 SV = 3 | 3,27164 | 0,659602 |
| P0C0L4 | Complement C4-A OS = Homo sapiens OX = 9606 GN = C4A PE = 1 SV = 2 | 1,03893 | 1,49116 |
| P07360 | Complement component C8 gamma chain OS = Homo sapiens OX = 9606 GN = C8G PE = 1 SV = 3 | 0,24517 | 0,503356 |
| Q9UGM5 | Fetuin-B OS = Homo sapiens OX = 9606 GN = FETUB PE = 1 SV = 2 | 1,40429 | 0,541632 |
| P02671 | Fibrinogen alpha chain OS = Homo sapiens OX = 9606 GN = FGA PE = 1 SV = 2 | 1,10486 | 0,59767 |
| O75636 | Ficolin-3 OS = Homo sapiens OX = 9606 GN = FCN3 PE = 1 SV = 2 | 1,00807 | 0,802906 |
| Q08380 | Galectin-3-binding protein OS = Homo sapiens OX = 9606 GN = LGALS3BP PE = 1 SV = 1 | 0,465231 | 0,6933 |
| P06396 | Gelsolin OS = Homo sapiens OX = 9606 GN = GSN PE = 1 SV = 1 | 0,511214 | 1,56289 |
| P00739 | Haptoglobin-related protein OS = Homo sapiens OX = 9606 GN = HPR PE = 2 SV = 2 | 1,34752 | 0,539945 |
| P01857 | Immunoglobulin heavy constant gamma 1 OS = Homo sapiens OX = 9606 GN = IGHG1 PE = 1 SV = 1 | 0,585063 | 0,669012 |
| P01742 | Immunoglobulin heavy variable 1-69 OS = Homo sapiens OX = 9606 GN = IGHV1-69 PE = 1 SV = 2 | 0,64299 | 0,872349 |
| A0A0B4J1V2 | Immunoglobulin heavy variable 2-26 OS = Homo sapiens OX = 9606 GN = IGHV2-26 PE = 3 SV = 1 | 0,33751 | 0,617746 |
| P04433 | Immunoglobulin kappa variable 3-11 OS = Homo sapiens OX = 9606 GN = IGKV3-11 PE = 1 SV = 1 | 1,30189 | 0,644815 |
| P01619 | Immunoglobulin kappa variable 3-20 OS = Homo sapiens OX = 9606 GN = IGKV3-20 PE = 1 SV = 2 | 1,54984 | 0,759295 |
| A0A0C4DH55 | Immunoglobulin kappa variable 3D-7 OS = Homo sapiens OX = 9606 GN = IGKV3D-7 PE = 3 SV = 5 | 1,82442 | 1,17608 |
| P06312 | Immunoglobulin kappa variable 4-1 OS = Homo sapiens OX = 9606 GN = IGKV4-1 PE = 1 SV = 1 | 0,870637 | 0,741953 |
| P0DOY2 | Immunoglobulin lambda constant 2 OS = Homo sapiens OX = 9606 GN = IGLC2 PE = 1 SV = 1 | 0,73101 | 0,509415 |
| P01703 | Immunoglobulin lambda variable 1-40 OS = Homo sapiens OX = 9606 GN = IGLV1-40 PE = 1 SV = 2 | 0,980606 | 0,997284 |
| P01700 | Immunoglobulin lambda variable 1-47 OS = Homo sapiens OX = 9606 GN = IGLV1-47 PE = 1 SV = 2 | 1,59502 | 0,521646 |
| P01701 | Immunoglobulin lambda variable 1-51 OS = Homo sapiens OX = 9606 GN = IGLV1-51 PE = 1 SV = 2 | 0,495094 | 1,1716 |
| Q14624 | Inter-alpha-trypsin inhibitor heavy chain H4 OS = Homo sapiens OX = 9606 GN = ITIH4 PE = 1 SV = 4 | 0,622172 | 0,533977 |
| P02750 | Leucine-rich alpha-2-glycoprotein OS = Homo sapiens OX = 9606 GN = LRG1 PE = 1 SV = 2 | 0,941312 | 0,739914 |
| P08571 | Monocyte differentiation antigen CD14 OS = Homo sapiens OX = 9606 GN = CD14 PE = 1 SV = 2 | 1,18636 | 0,777581 |
| P02776 | Platelet factor 4 OS = Homo sapiens OX = 9606 GN = PF4 PE = 1 SV = 2 | 0,896119 | 0,575848 |
| P20742 | Pregnancy zone protein OS = Homo sapiens OX = 9606 GN = PZP PE = 1 SV = 4 | 0,918109 | 1,33271 |
| P02760 | Protein AMBP OS = Homo sapiens OX = 9606 GN = AMBP PE = 1 SV = 1 | 1,17521 | 0,568105 |
| Q92954 | Proteoglycan 4 OS = Homo sapiens OX = 9606 GN = PRG4 PE = 1 SV = 3 | 0,841435 | 1,25299 |
| P0DJI8 | Serum amyloid A-1 protein OS = Homo sapiens OX = 9606 GN = SAA1 PE = 1 SV = 1 | 0,591495 | 0,891718 |
| P02743 | Serum amyloid P-component OS = Homo sapiens OX = 9606 GN = APCS PE = 1 SV = 2 | 1,50171 | 1,03638 |
| P62979 | Ubiquitin-40S ribosomal protein S27a OS = Homo sapiens OX = 9606 GN = RPS27A PE = 1 SV = 2 | 1,73161 | 1,07562 |