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. 2020 Aug 28;8:853. doi: 10.3389/fcell.2020.00853

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Copyright © 2020 Xin, Lv, Liu, Jing and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Opa1 activates mitophagy and mitochondrial biogenesis in hypoxia-treated cardiomyocytes. (A–C) Analysis of ATG5, Parkin, and Beclin1 expression through qPCR. (D,E) Mitophagy analysis in living cardiomyocytes by mt-Keima reporter assay. (F,G) Analysis of Tfam and PGC1α expression through qPCR. ^∗p < 0.05.