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. 2020 Aug 28;11:962. doi: 10.3389/fgene.2020.00962

FIGURE 8.

FIGURE 8

Circ-MEMO1 interference restrains the NSCLC tumor growth in vivo. BALB/c nude mice were divided into sh-NC group (n = 7) and sh-circ-MEMO1 group (n = 7). A549 cells stably expressing sh-NC or sh-circ-MEMO1 were subcutaneously injected into the right back of the nude mice in the corresponding group. (A) The tumor volume was measured after injection for 7 days every 3 days with the formula: length × width2 × 0.5. (B) Tumor weight in sh-NC group and sh-circ-MEMO1 group was measured with an analytical balance. (C,D) The expression of circ-MEMO1 and miR-101-3p in two groups was detected by qRT-PCR. (E) Western blot assay was used to detect the protein expression of KRAS in two groups. *P < 0.05.