Table 2.
Populations, cell types, number of significant genes, and corresponding biomarkers identified from single-cell sequencing of peripheral axolotl immune cells. The top 5 sig genes are annotated genes that were the most significantly enriched in each population.
| Population | Cell Type | Sig Genes | Top 5 Sig Genes |
|---|---|---|---|
| Pop1 | Thrombocyte | 286 | thbs1, f2rl3, gp9, cald1, wipf3 |
| Pop2 | B-cell | 76 | cd5l, igll5, atp1b3, rpl22l1, hvcn1 |
| Pop3 | T-cell | 30 | trac, ccl19, psapl1, igll59, gzmb |
| Pop4 | Erythrocyte | 34 | hba, hbb, hbg1, alas2, slc4a1 |
| Pop5 | Neutrophil | 212 | mmp1, chit1, camp, cebpe, btn1a1 |
| Pop6 | Macrophage | 201 | cr2, c4a, siglec1, fabp1, lta4h |
| Pop7 | Myeloid-like | 185 | lect2, epx, lgals1, prtn3, psap |