Table 1.

Detailed information of the included studies (8–62).

	First author	Country	Sample	Method	Total patient number	Specimen positivity	Age range (years)	Sex	NOS
1	Wu	China	R, F	RT-PCR	74	41 F+	40–52	35 Fem 39 Mal	9
2	Zhang Y	China	R, F	RT-PCR	15	5 F+	37 (10–73)	7 Fem 8 Mal	8
3	Xu	China	R, F	RT-PCR	10	8 F+	0.2–15.7	4 Fem 6 Mal	8
4	Xing YH	China	R, F	RT-PCR	3	3 F+	1.5–6	1 Fem 2 Mal	8
5	Chen	China	R, F, U	RT-PCR	42	28 F+	51 (42.75–62)	24 Fem 18 Mal	9
6	Lo	China	R, F, U	RT-PCR	10	10 F+	54 (27–64)	7 Fem 3 Mal	9
7	Nicastri	Italy	R, F, U, O	RT-PCR	1	1 F+	29	1 Mal	7
8	Young	Singapore	R, F, Bl, U	RT-PCR	8	4 F+	n. a.	n. a.	7
9	Holshue	USA	R, F, Bl	RT-PCR	1	1 F+	35	1 Mal	7
10	Cai	China	R, F, Bl, U	RT-PCR	6	6 F+	0.3–10.9	4 Fem 2 Mal	8
11	Zhang JC	China	R, F	RT-PCR	14	5 F+	18–87	7 Fem 7 Mal	8
12	Zeng L	China	R, F	RT-PCR	1	1 F+	0.46	1 Mal	7
13	Yang Z	China	R, F	RT-PCR	3	3 F+	25–62	1 Fem 2 Mal	7
14	Xiao F	China	R, F	RT-PCR	73	39 F+	43 (0.83–7)	32 Fem 41 Mal	7
15	Zheng	China	R, F, Bl, U	RT-PCR	96	55 F+, 39 Bl+, 1 U+	55 (44.3–64.8)	38 Fem 58 Mal	8
16	Pan	China	R, F, U	RT-PCR	11	–	n. a.	n. a.	7
17	Cheng	Taiwan	R, F, U	RT-PCR	1	–	55	1 Fem	7
18	Kim	Korea	R, F, Bl, U	RT-PCR	2	–	35–55	1 Fem 1 Mal	8
19	Qian	China	R, F	RT-PCR	1	1 F+	47	1 Mal	7
20	Xing	China	R, F	RT-PCR	1	–	40	1 Mal	7
21	Tang	China	R, F	RT-PCR	1	1 F+	10	1 Mal	7
22	Tan	China	R, F, Bl	RT-PCR	4	3 F+	3.5–9	3 Fem 1 Mal	8
23	Mansour	Lebanon	R, F, U	RT-PCR/ cultures	1	–	1.41	1 Fem	7
24	Chen	China	R, F	RT-PCR	22	12 F+	2–64	8 Fem 14 Mal	9
25	Han	Korea	R, F, Bl, U	RT-PCR	2	1 F+ Bl+ U+ Sal+, 1 F+	55	2 Fem	7
26	Zhang T	China	R, F	RT-PCR	3	3 F+	6–9	3 Mal	8
27	Yuang	China	R, F	RT-PCR	6	6 F+	36–71	4 Fem 2 Mal	8
28	Liu	China	R, F	RT-PCR	4	4 F+	8–46	2 Fem 2 Mal	8
29	Li J	China	R, F, Bl, U, Vag, Mil	RT-PCR	13	3 F+	1–73	7 Fem 6 Mal	8
30	Jiang	China	R, F	RT-PCR	1	1 F+	8	1 Fem	7
31	Paoli	Italy	R, U, Sp	RT-PCR	1	–	31	1 Mal	7
32	Seah	Singapore	R, O	RT-PCR/viral isolation	17	–	20–75	6 Fem 11 Mal	7
33	Lescure	France	R, F, Bl, U, O	RT-PCR/viral isolation	5	2 F+, 1 Bl+	30–80	2 Fem 3 Mal	9
34	Wölfel	Germany	R, F, Bl, U	RT-PCR	16	8 F	35 (2–58)	4 Fem 12 Mal	7
35	Kujawski	USA	R, F, Bl, U	RT-PCR	10	6 F+, 1 F+ Bl+	53 (21–68)	3 Fem 7 Mal	9
36	Su	China	R, F	RT-PCR	4	4 F+	0.9–3.6	2 Fem 2 Mal	8
37	Sun	China	R, U	RT-PCR	1	1 U+	72	1 Mal	7
38	Cheung	China	R, F	RT-PCR	59	9 F+	22–96	32 Fem 27 Mal	6
39	Zhang W	China	R, F, Bl	RT-PCR	16	10 F+	n.a.	n.a.	7
40	Ling	China	R, F, U	RT-PCR	66	66 F+ (4/58 U+)	34–62	38 Fem 28 Mal	7
41	Lei	China	R, F	RT-PCR	7	4 F+	n.a.	n.a.	6
42	Wu	China	R, F, Bl	RT-PCR	132	36 F+, 4 Bl+	66.7 ± 9.1	60 F 72 M	7
43	Ma	China	R, F	RT-PCR	8	5 F+	0.9–39	6Fem 2 Mal	7
44	Fang	China	R, F, Bl, O	RT-PCR	32	23 Bl+; 5 O+	41 (34–54)	16 Fem 16 Mal	7
45	Wei	China	R, F	RT-PCR	84	28 F+	37 (24–74)	56 Fem 28 Mal	7
46	Qian GQ	China	R, F	RT-PCR	91	2 F+	5–96	54 Fem 37 Mal	8
47	Peng	China	R, F, Bl, U	RT-PCR	7	1 F+, 1 F+ Bl+1 Bl+, 1 U+	27–49	4 Fem 3 Mal	7
48	Yun	China	R, F, Bl, O	RT-PCR	32	8 F+	50 (37–66)	17 Fem 15 Mal	7
49	Wang	China	R, U	RT-PCR	116	53 U+	54 (38-69)	49 Fem 67 Mal	7
50	Yu	China	R, Bl, U	RT-PCR/dd-PCR	76	4 Bl- 14 U-	40 (32–63)	38 Fem 38 Mal	8
51	Lin	China	R, F, Biop	RT-PCR	65	31 F+, 3/6 Biop+	n.a.	n.a.	7
52	Wang	China	R, F, Sew	RT-PCR	2	1 F+, Sew+	n.a.	n.a.	6
53	Xie	China	R, F, Bl, U	RT-PCR	9	8 F+	18–62	5 Fem 4 Mal	7
54	Huang J	China	R, Bl	RT-PCR/NGS	41	6 Bl+	49 (41–58)	11 Fem 30 Mal	8
55	Wang W	China	R, F, Bl	RT-PCR	20	6 F+, 2 Bl+	n.a.	n.a.	7

NOS, Newcastle—Ottawa Quality Assessment Scale; R, respiratory tract swabs; F, fecal samples; U, urine samples; Bl, blood; O, ocular samples; Vag, vaginal samples; Mil, Breast Milk; Biop, biopsies; Sew, sewage; +, number of positive samples; Fem, female; Mal, male; n. a., not available.