Table 3.

Effect of Triplicate Image Averaging on Quantitative Indices of Peripapillary Blood Flow

	Glaucoma Suspect Eyes				Glaucoma Eyes
Index	Single Image*	2 Frames Averaged*	3 Frames Averaged*	p- value†	Single Image*	2 Frames Averaged*	3 Frames Averaged*	P- value†
Vessel Area Density	0.479 (0.476, 0.482)	0.472 (0.468, 0.476)	0.467 (0.463, 0.472)	<0.001	0.447 (0.440, 0.455)	0.429 (0.419, 0.440)	0.416 (0.404, 0.427)	<0.001
Vessel Skeleton Density	0.187 (0.186, 0.189)	0.183 (0.182, 0.185)	0.181 (0.180, 0.183)	<0.001	0.176 (0.173, 0.179)	0.169 (0.165, 0.173)	0.163 (0.159, 0.168)	<0.001
Flux	0.210 (0.206, 0.213)	0.201 (0.197, 0.205)	0.196 (0.192, 0.200)	<0.001	0.177 (0.170, 0.183)	0.166 (0.160, 0.173)	0.160 (0.153, 0.166)	<0.001

^*Values listed as mean (95% confidence interval).

^†P-values obtained from Wilcoxon signed-rank test comparing single frame value to 3-frame averaged image value