Table 2.

Cox multivariable regression of independent predictors of survival, with time to adjuvant therapy modeled as a categorical variable by quartile.

Predictor	Hazard Ratio	95% Confidence Interval		p-value
		Lower	Upper
Age (per year)	1.01	1.00	1.02	0.03
Sex (female)	0.93	0.76	1.13	0.45
Race (reference: White)
Black	1.15	0.83	1.59	0.41
Other	1.01	0.63	1.62	0.96
Year of diagnosis (per year)	0.94	0.92	0.96	<0.001
Charlson-Deyo Comorbidity (CDCC) score (reference: 0)
1	1.08	0.92	1.27	0.34
2+	1.40	1.06	1.85	0.02
Insurance status (reference: private)
Government	1.20	1.01	1.42	0.03
None	1.19	0.70	2.02	0.52
Facility location (reference: metro)
Urban	1.28	1.07	1.54	0.007
Rural	1.12	0.73	1.73	0.60
Facility type (reference: non-academic)
Academic/Research Program	0.97	0.84	1.11	0.63
Pathologic stage (reference: 1)
2	2.36	1.25	4.48	0.008
3	4.04	2.14	7.62	<0.001
Margin status (reference: R0)
R1	1.65	1.37	1.99	<0.001
R2	1.29	0.53	3.16	0.58
Squamous histology	0.99	0.80	1.23	0.94
Perioperative radiation (reference: none)
Induction	0.49	0.83	1.13	0.17
Adjuvant	0.97	0.83	1.13	0.68
Length of stay	1.00	0.99	1.01	0.77
30-day readmission	1.27	0.97	1.65	0.08
Time to adjuvant therapy (reference: Q1 ≤45 days)
Q2 46–60 days	1.08	0.90	1.31	0.40
Q3 61–75 days	1.17	0.96	1.43	0.12
Q4 >75 days	1.07	0.89	1.30	0.46