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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Equine Vet J. 2020 Mar 25;52(6):841–847. doi: 10.1111/evj.13254

Fig 1: Histological and in situ hybridisation results from Case 1 (a and b) and Case 3 (c and d).

Fig 1:

Loss of centrilobular hepatocytes (asterisk) and an island of remnant hepatocytes (arrow), 200x, HE.

Cytoplasmic vacuolation of hepatocytes (arrow), 400x, HE.

Hybridisation of viral nucleic acid is highest in periportal regions and reduced in centrilobular regions where hepatocytes are lost (asterisk in inset), 200x, 1000x inset, EqPV-H in situ hybridisation.

Red puncta of hybridisation within the cytoplasm of multiple hepatocytes, 600x, EqPV-H in situ hybridisation.