. Author manuscript; available in PMC: 2021 Jul 1.

Published in final edited form as: Alzheimer Dis Assoc Disord. 2020 Jul-Sep;34(3):212–219. doi: 10.1097/WAD.0000000000000385

Table 3.

Parameter estimates for cognitive outcomes: AHA exercise groups.

Effect	APOE: Verbal Fluency	APOE: Episodic Memory	APOE: Processing Speed	APOE: Executive Functions	BDNF: Verbal Fluency	BDNF: Episodic Memory	BDNF: Processing Speed	BDNF: Executive Functions
Time	−.04 (.007)^*	−.02 (.008)^*	−.08 (.01)^*	−.02 (.006)^*	−.04 (.007)^*	−.03 (.007)^*	−.08 (.01)^*	−.02 (.006)^*
Exercise group	.23 (.09)^*	.05 (.08)	.06 (.10)	.05 (.08)	.21 (.09)^*	.05 (.08)	.05 (.10)	.03 (.08)
APOE or BDNF Genotype	−.02 (.09)	−.02 (.10)	−.04 (.10)	.001 (.08)	−.02 (.09)	−.002 (.08)	−.03 (.10)	.02 (.08)
CDR change	−.84 (.10)^*	−1.25 (.09)^*	−.54 (.11)^*	−.56 (.09)^*	−.87 (.10)^*	−1.28 (.09)^*	−.45 (.11)^*	−.57 (.09)^*
Sex	.27 (.09)^*	.35 (.08)^*	.23 (.10)^*	.15 (.09)	.26 (.09)^*	.37 (.08)^*	.21 (.11)^*	.10 (.09)
Age	−.009 (.005)	−.001 (.005)	.006 (.006)	−.007 (.005)	−.007 (.005)	.001 (.005)	.01 (.006)	−.005 (.005)
Education	.08 (.02)^*	.08 (.01)^*	.05 (.02)^*	.06 (.01)^*	.08 (.02)^*	.08 (.01)^*	.05 (.02)^*	.06 (.01)^*
Health composite	−.02 (.04)	.001 (.03)	−.09 (.04)^*	−.01 (.04)	−.02 (.04)	.02 (.03)	−.09 (.04)^*	−.02 (.04)
Exercise - 1^st Outcome Delay	.03 (.04)	−.11 (.04)^*	−.02 (.06)	.06 (.04)	.03 (.05)	−.09 (.04)^*	−.02 (.06)	.04 (.04)
Time × Exercise	---	---	.04 (.02)^*	---	---	---	.04 (.02)^*	---
Exercise × Genotype	---	---	---	---	---	---	---	---
Time × Genotype	---	−.03 (.01)^*	---	---	---	---	---	---
Time × Exercise × Genotype	---	---	---	---	---	---	---	---

Notes: Data represent parameter estimates (standard errors) for the final model;

= p<.05,

^†

= p<.06; --- = not included in final model.