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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Mol Cancer Res. 2020 Jun 8;18(9):1278–1289. doi: 10.1158/1541-7786.MCR-20-0046

Table 2. Ingenuity canonical pathways of MSGE common to spontaneous models of metastasis.

Ingenuity Pathway Analysis results showing the pathways populated by MSGE common to both spontaneous allograft and GEMM models. Significance of enrichment for this pathway in each the gene set is indicated by the -log(p-value) where >1.3 is significant.

-log(p-value)
Nicotine Degradation II 6.98
Estrogen Biosynthesis 5.23
Acetone Degradation I (to Methylglyoxal) 5.13
Bupropion Degradation 4.4
Agranulocyte Adhesion and Diapedesis 3.94
Nicotine Degradation III 3.66
Hepatic Fibrosis / Hepatic Stellate Cell Activation 3.35
Atherosclerosis Signaling 3.23
Intrinsic Prothrombin Activation Pathway 3.04
Cellular Effects of Sildenafil (Viagra) 2.91
Granulocyte Adhesion and Diapedesis 2.88