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TcdA decreases cell proliferation in mouse ileum crypts. (A) Percentage of the cells showing positive Ki67 immunostaining. Data are the means ± SEM in 6–8 microscope fields per sample (n = 5 mice per group); Student’s t-test. (B) Representative immunohistochemical images of Ki67 levels in mouse ileum challenged with PBS (control) or TcdA (10 μg) for 4 h.
