Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
An indirect mechanism to sense pathogen‐associated activities. DPP8/9 inhibitors, T gondii infection and metabolic inhibitors may induce the same perturbation within cells, which in turn activates an E3 ligase to ubiquitinate and degrade the NLRP1 N‐terminus. In this model, unlike the “decoy” model, NLRP1 indirectly senses pathogen‐associated activities
