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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Neurochem Int. 2020 Jul 8;139:104788. doi: 10.1016/j.neuint.2020.104788

Fig. 4.

Fig. 4.

ENOblock treatment induces neuroprotection in SCI. (A) Neurofilament protein (NFP, green) and DAPI (blue) nuclear staining of SCI tissue at the injury site. Panel shows representative images taken at 20× magnification. (B) Mean fluorescence intensity from three representative areas shows significantly decreased NFP expression in vehicle treated tissue. There is also a significant increase in NFP expression indicating the recovery with ENOblock treatment as compared to vehicle treated controls (paired t-test, two-tailed, *p < 0.05, **p<0.01; n=3–5). (C) Chondroitin sulfate proteoglycan (CSPG, red; arrows) and DAPI (blue) nuclear staining of SCI tissue at the injury site. Representative images were taken at 20× magnification. (D) Mean fluorescence intensity shows a significant increase in CSPG in vehicle treated rats that is significantly reduced with ENOblock treatment (paired t-test, two-tailed, *p < 0.05; n=4–5).