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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Exp Eye Res. 2020 May 23;197:108079. doi: 10.1016/j.exer.2020.108079

Figure 4. 2DG pre-treatment reduces intraocular inflammation in Staphycocccal endophthalmitis.

Figure 4.

WT C57BL/6 mice (n=10) were pretreated overnight with intravitreal injections of 2DG (25 μg/eye) followed by intravitreal injection of S. aureus. 24 h post-infection eyes were enucleated, homogenized and subjected to ELISA for cytokine quantification (A), Western blotting for pERK1/2, ERK1/2 and HSP90 proteins (B), and bacterial burden estimation (C). A one-way ANOVA with Tukey post hoc test was used to determine statistical significance. **p<0.01, ***p<0.001, ns: not significant. Data represent mean ± SD.