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. Author manuscript; available in PMC: 2021 Sep 15.
Published in final edited form as: J Immunol. 2020 Aug 7;205(6):1633–1643. doi: 10.4049/jimmunol.2000440

Figure 2. Sectm1a deficiency enhances systemic inflammation and bacterial burden.

Figure 2.

(A-E) Serum levels of cytokines (A: IL-1β; B: IL-6; C: IL-10; D: TNF-α; E: MCP-1) were measured in WT and Sectm1a-KO mice at 12 h after CLP surgery (n = 5–7). (F-G) Bacterial burdens in both peritoneal lavage fluid (F) and blood (G) were compared between WT mice and Sectm1a-KO mice at 18 h post-CLP operation (n = 8). (H-I) At 24 h post-CLP surgery, spleen and lung were collected from WT mice and Sectm1a-KO mice, and bacterial burdens in these tissues were compared between two models (n = 5–7). Data are representative of two independent experiments. All results are presented as mean ± SEM and analyzed by student’s t test or two-way ANOVA.