TABLE 1.
Baseline Study Participant Demographic and Clinical Characterization.
| N | 716 |
|---|---|
| Average # of study visits | 2.5 (range: 1, 13) |
| N with structural DTI | 365 |
| Average # imaging visits | 1.6 (range: 1, 5) |
| Demographics | Mean (SD) or Percent (%) |
|---|---|
| Age, years | 67.9 (8.6) |
| Sex, % (N) female | 56.8% (407) |
| Education, years | 17.6 (3.9) |
| Race/ethnicity | 94.3% White |
| 4% Asian (Chinese, Japanese, Filipino) | |
| 0.4% Asian Indian | |
| 0.2% Black | |
| 1.1% Other/Refuse to state |
| Baseline Mood Assessment | Median (IQR) (range) |
|---|---|
| Geriatric Depression Scale (GDS) | 2 (0, 1, 5) (0–24) |
| GDS Subscales (Weighted Averages) | Mean (SD) |
|---|---|
| Dysphoria | 0.097(0.16) |
| Negative mood | 0.091 (0.18) |
| Apathy | 0.160(0.21) |
| Hopelessness | 0.052 (0.16) |
| Social withdrawal | 0.092 (0.15) |
| Decreased concentration | 0.310(0.15) |
| Cognitive impairment | 0.092 (0.19) |
| Baseline Cognition | Mean (SD) (range) or Median (IQR) |
|---|---|
| Clinical Dementia Rating (CDR) | 0 |
| Mini-Mental State Exam (MMSE) | 29 (1.1) (25, 30) |
DTI: Diffuse Tensor Imaging; GDS: Geriatric Depression Scale; CDR: Clinical Dementia Rating; MMSE: Mini-Mental State Exam.