F4/80 is localized in the cochlea in
Ifnar1−/−
ZIKV infected mice. F4/80 is not localized in the cochlea in vehicle-treated
mice (A, B). F4/80 is upregulated in the cochlear epithelium (arrowheads C, D)
and in cells beneath the basilar membrane (arrows; C, D, E, F) following ZIKV
infection. Myosin VIIa staining of inner (gray arrow, B and D) and outer (open
arrow, B and D) shows that hairs cells are not double labeled with F4/80
following vehicle treatment (B) or ZIKV infection (D). The gelatinous matrix of
the tectorial membrane shows non-specific labeling (A-D). DAPI counterstains are
shown (B, D, F). Scale bar for A-E in F.