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. Author manuscript; available in PMC: 2020 Sep 11.
Published in final edited form as: Cell Syst. 2020 Jul 2;11(2):176–185.e6. doi: 10.1016/j.cels.2020.06.006

Figure 1. Physiological versus Epigenetic Change during Development and Aging.

Figure 1.

Aging yields similar physiological changes in humans and dogs, yet these changes occur along different time scales. Are these different timescales reflected in the progression of epigenetic changes observed during aging? If so, is this progression consistent with the adage “one dog year equals seven human years,” or does it suggest a different cross-species alignment of time?