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. Author manuscript; available in PMC: 2020 Sep 11.
Published in final edited form as: Leukemia. 2020 Feb 24;34(9):2342–2353. doi: 10.1038/s41375-020-0764-6

Figure 6. Pathway analysis indicates IL-10 signaling is enriched in IBR+VEN resistant samples.

Figure 6.

A. The IL-10 signaling pathway is enriched in IBR+VEN resistant samples as represented in the volcano plot depicting the relative expression of ~22,000 genes. Genes involved in the IL-10 signaling pathway are highlighted by blue dots; differentially expressed genes with an adjusted p-value < 0.001 are labeled. Red dashed line indicates p-value of 0.01. B. Dot plot comparisons of expression for select DE inflammatory signaling pathway genes.