Table 3.

Cox’s proportional hazard models for bone metastasis and other known prognostics factors.

		PFS Overall		PFS Immunotherapy		PFS Targeted Therapy
		HR	P	HR	P	HR	P
Univariable	Bone Metastasis	1.30	0.009	1.01	0.933	1.41	0.129
Multivariable	Performance Status	1.34	0.001	1.38	0.009	1.04	0.825
	Number of Metastatic Sites	1.00	0.906	0.97	0.306	1.08	0.094
	High LDH	1.74	<0.001	1.52	0.018	1.49	0.179
		OS Overall		OS Immunotherapy		OS Targeted Therapy
		HR	P	HR	P	HR	P
Univariable	Bone Metastasis	1.81	<0.001	1.34	0.067	1.77	0.031
Multivariable	Bone Metastasis	1.38	0.047	1.11	0.611	1.96	0.048
	Performance Status	1.82	<0.001	1.98	<0.001	1.38	0.060
	Number of Metastatic Sites	1.06	0.017	1.04	0.236	1.09	0.091
	High LDH	1.62	0.003	1.55	0.041	1.33	0.354