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. Author manuscript; available in PMC: 2021 Sep 25.
Published in final edited form as: Int J Pharm. 2020 Jul 10;587:119624. doi: 10.1016/j.ijpharm.2020.119624

Table 2.

Volume recovered (mL) and amount of drug extracted in the recovered volume (mg) after incubation with water at room temperature under static, agitating conditions and after thermal manipulation. (mean ± SD, n = 3).

Manipulation condition Volume recovered (out of 10 mL) and amount of drug extracted (mg) in the recovered volume
F1 F2 F3 F4
Static Volume recovered (mL) 8.7 ± 0.15 7.0 ± 0.19 8.8 ± 0.11 8.7 ± 0.20
Amount of drug extracted (mg) 5.41 ± 0.33 0.97 ± 0.44 1.38 ± 0.30 4.26 ± 0.26
Agitation Volume recovered (mL) 8.4 ± 0.29 5.8 ± 0.41 8.0 ± 0.37 8.7 ± 0.26
Amount of drug extracted (mg) 24.99 ± 0.32 9.85 ± 0.55 10.95 ± 0.22 21.36 ± 0.29
Thermal (oven) Volume recovered (mL) 8.6 ± 0.49 6.1 ± 0.59 7.5 ± 0.50 7.9±0.28
Amount of drug extracted (mg) 28.58 ± 1.62 12.16 ± 3.29 26.06 ± 1.76 23.71 ± 2.09