Table 1.
Correlation of SRD5A1 expression and clinical characteristics in CRC.
| Characteristic | n | SRD5A1 expression (%) | Pearson χ2 | P | |
|---|---|---|---|---|---|
| High | Low | ||||
| Total | 100 | 58 (58) | 42 (42) | ||
| Age | 0.630 | 0.527 | |||
| ≥60 | 36 | 19 (52.78) | 17 (47.22) | ||
| <60 | 64 | 39 (60.94) | 25 (39.06) | ||
| Sex | 0.725 | 0.412 | |||
| Female | 38 | 20 (52.63) | 18 (47.37) | ||
| Male | 62 | 38 (61.29) | 24 (38.71) | ||
| Histological type | 0.012 | 1.000 | |||
| Ulcer type | 72 | 42 (58.33) | 30 (41.67) | ||
| Uplift type | 28 | 16 (57.14) | 12 (42.86) | ||
| Tumor site | 0.001 | 1.000 | |||
| Right colon | 12 | 7 (58.33) | 5 (41.67) | ||
| Left colon | 88 | 51 (57.95) | 37 (42.05) | ||
| Tumor size (cm) | 0.029 | 1.000 | |||
| ≥5 | 49 | 28 (57.14) | 21 (42.86) | ||
| <5 | 51 | 30 (58.82) | 21 (41.18) | ||
| Pathological grade | 9.044 | 0.004** | |||
| I–II | 49 | 21 (9.71) | 28 (90.29) | ||
| III–IV | 51 | 37 (32.26) | 14 (67.74) | ||
| Lymph node metastasis | 9.873 | 0.002** | |||
| No | 53 | 23 (43.40) | 30 (56.60) | ||
| Yes | 47 | 35 (74.47) | 12 (25.53) | ||
| Distant metastasis | 5.953 | 0.021* | |||
| No | 85 | 45 (0.00) | 40 (100.00) | ||
| Yes | 15 | 13 (17.45) | 2 (82.55) | ||
| Survival status | 6.787 | 0.034* | |||
| Death | 20 | 16 (80.00) | 4 (20.00) | ||
| Tumor survival | 6 | 5 (83.33) | 1 (16.67) | ||
| Disease-free survival | 70 | 36 (51.43) | 34 (48.57) | ||
*
P < 0.05,
**
P < 0.01,
***P < 0.001.