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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Biosens Bioelectron. 2020 May 16;165:112289. doi: 10.1016/j.bios.2020.112289

Figure 2.

Figure 2.

Detection of HIV-1 protease in a PET nanopore. Typical 10-s single channel recording trace segments of a) 100 ng/mL HIV-1 protease in the unmodified PET nanopore, b) 10 ng/mL and c) 100 ng/mL HIV-1 protease in the amine-modified PET nanopore; d) selective individual short-lived and long-lived events; and the corresponding event (e) amplitude histogram and residence time histograms of (f) short-lived and (g) long-lived events of Figure 2c. The experiments were performed at +800 mV in a solution comprising 1 M KCl and 10 mM Tris (pH 7.5). An uninterrupted 2-min single-channel recording trace of 100 ng/mL HIV-1 PR in the modified PET nanopore was displayed in Figure S4.