. Author manuscript; available in PMC: 2021 Sep 1.

Published in final edited form as: Clin Lymphoma Myeloma Leuk. 2020 Apr 7;20(9):596–601. doi: 10.1016/j.clml.2020.03.012

Table 2.

Univariate and Multivariate Analysis for PFS and OS

	Univariate		Multivariate
Characteristic	HR (95% CI)	P	HR (95% CI)	P
PFS
Age ≥65 years	1.33 (1.16-1.53)	<.0001^*	1.46 (1.25-1.71)	<.0001^*
R-ISS (1-2 vs. 3)	0.49 (0.40-0.60)	<.0001^*	0.49 (0.39-0.62)	<.0001^*
Creatinine >2 mg/dL	1.4 (1.57-1.71)	.0006^*	0.93 (0.72-1.22)	.63
BMPC% ≥60%	1.4 (1.24-1.62)	<.0001^*	1.23 (1.03-1.52)	.015^*
OS
Age ≥65 years	1.88 (1.60-2.21)	<.0001^*	2.23 (1.84-2.70)	<.0001^*
R-ISS (1-2 vs. 3)	0.38 (0.31-0.48)	<.0001^*	0.41 (0.32-0.52)	<.0001^*
Creatinine >2 mg/dL	1.66 (1.34-2.07)	<.0001^*	1.18 (0.88-1.57)	.25
BMPC% ≥60%	1.44 (1.23-1.69)	<.0001^*	1.24(1.03-1.49)	.02^*

Abbreviations: BMPC% = bone marrow plasma cell percentage; CI = confidence interval; HR = hazard ratio; OS = overall survival; PFS = progression-free survival; R-ISS = Revised International Staging System.

Statistically significant (P < .05).