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. Author manuscript; available in PMC: 2021 Sep 15.
Published in final edited form as: J Immunol. 2020 Aug 12;205(6):1601–1607. doi: 10.4049/jimmunol.2000094

Figure 3. Influenza infection abolishes AM-mediated bacterial clearance during secondary pneumococcal infection.

Figure 3.

(A) Lung bacterial burdens (mean±SD), (B) BALF CD11c+Siglec-F+ AM numbers (mean±SEM), (C) the numbers of CD11b+Ly6C+ monocytes (Mo) and CD11b+Ly6G+ neutrophils (PMN), (D) the levels of TNF-α and IFN-γ (mean±SEM), and (E) lung viral burdens (mean±SEM) 24 h after i.n. challenge of naïve (Spn) or day seven PR8-infected (PR8/Spn) B6 WT and Csf2rb−/− mice (n ≥ 5 mice/group) with Spn. ***P<0.001, Tukey’s multiple comparisons test. Data shown are representative of two independent experiments.