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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Cancer Res. 2020 Jul 8;80(17):3606–3619. doi: 10.1158/0008-5472.CAN-20-0108

Figure 5: Eliminating DOXO-induced senescent cells prevents malignant tumor development.

Figure 5:

Representative images of H&E staining of the skin (top panels) and tumors (bottom panels) in PBS + PBS, PBS + GCV, DOXO + PBS, DOXO + GCV treated-groups (200 μm). (B-D) In the same 4 groups (PBS + PBS: n =9, PBS + GCV: n=7, DOXO + PBS: n=11, DOXO + GCV: n=7), representative IHC images for Ki-67 (B), vimentin (C) and CD-31 (D) (50 μm) with the corresponding quantification of percent positive cells in the right panels. Shown are means ±SEM; *p<0.05, **p<0.01, ***p<0. 001 (one-way ANOVA, Sidak’s multiple comparisons test was used post-analyses).

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