Table 3.
The p values of student t-test for selected peaks between the case and control groups. Metabolites with multiple peaks were reserved to study the method influence to the t-test p values. The p values were ordered from smallest to largest based on the manual method.
| ppm | No lb | 06 lb | 1 lb | 2 lb | Manual | |
|---|---|---|---|---|---|---|
| Cholate | 0.93 | 1.82E-04 | 6.78E-05 | 3.13E-05 | 3.64E-05 | 6.19E-05 |
| Leucine | 1.71 | 3.65E-02 | 2.20E-05 | 2.34E-03 | 8.11E-05 | 2.26E-03 |
| Leucine | 0.95 | 1.16E-03 | 4.41E-03 | 6.97E-03 | 6.19E-03 | 2.67E-03 |
| Isoleucine | 0.94 | 5.57E-03 | 1.31E-02 | 1.04E-02 | 5.80E-03 | 4.08E-03 |
| Butyrate | 1.61 | 7.42E-03 | 2.74E-03 | 2.71E-03 | 2.15E-03 | 5.87E-03 |
| Leucine | 1.76 | 2.35E-02 | 7.31E-03 | 9.01E-03 | 8.30E-03 | 9.82E-03 |
| Leucine | 1.74 | 2.68E-02 | 1.01E-02 | 1.05E-02 | 9.01E-03 | 1.08E-02 |
| Leucine | 1.76 | 1.75E-02 | 9.04E-03 | 1.14E-02 | 1.02E-02 | 1.21E-02 |
| Saccharopine | 3.08 | 1.23E-02 | 1.27E-02 | 1.19E-02 | 1.11E-02 | 1.26E-02 |
| Trimethylamine | 2.93 | 4.83E-01 | 3.79E-03 | 9.08E-03 | 1.07E-02 | 1.35E-02 |
| Trimethylamine | 2.90 | 3.35E-02 | 1.92E-02 | 2.28E-02 | 2.14E-02 | 1.61E-02 |
| Valine | 0.98 | 4.66E-02 | 3.17E-02 | 3.09E-02 | 3.03E-02 | 3.70E-02 |
| Isoleucine | 3.68 | 1.80E-01 | 1.61E-02 | 1.42E-02 | 1.77E-02 | 4.20E-02 |
| Leucine | 0.98 | 4.74E-02 | 9.60E-02 | 7.15E-02 | 7.25E-02 | 5.04E-02 |
| Ethanol | 3.65 | 5.67E-02 | 3.48E-02 | 3.54E-02 | 3.83E-02 | 5.23E-02 |
| Lactate | 4.13 | 2.02E-01 | 1.88E-02 | 2.52E-02 | 1.59E-02 | 5.42E-02 |
| Glutamate | 2.02 | 8.75E-02 | 6.82E-01 | 1.94E-01 | 4.65E-01 | 5.87E-02 |
| Threonine | 4.26 | 5.05E-01 | 8.05E-02 | 5.44E-02 | 1.77E-02 | 7.35E-02 |
| Lactate | 1.34 | 1.72E-01 | 5.37E-02 | 5.70E-02 | 5.55E-02 | 8.01E-02 |
| Average | 1.02E-01 | 5.77E-02 | 3.05E-02 | 4.20E-02 | 2.83E-02 |