Table 1.
Demographic and clinical characteristics of the participants.
| Characteristics | No Dementia | Dementia | Combined |
|---|---|---|---|
| N | 353 | 301 | 654 |
| Age at death, years (SD) | 89.3 (6.71) | 91.1 (6.52) | 90.1 (6.67) |
| Male, n (%) | 99 (28) | 81 (27) | 180 (28) |
| Education, years (SD) | 15.7 (3.7) | 15.6 (3.5) | 15.7 (3.6) |
| Median length of follow-up, years | 7.9 | 8.0 | 8.0 |
| Median time between last clinical evaluation and death, years | 0.75 | 0.57 | 0.67 |
| Mini-mental State Examination (MMSE), mean (SD) | 26.7 (2.6) | 11.4 (8.4) | 19.8 (9.7) |
| Heart disease, n (%) | 81 (23) | 45 (15) | 126 (19) |
| Hypertension, n (%) | 251 (71) | 211 (70) | 462 (71) |
| Diabetes, n (%) | 85 (24) | 60 (20) | 145 (22) |
| Smoking, n (%) | 124 (35) | 90 (30) | 214 (33) |
| Systolic blood pressure, mm Hg (SD) | 128 (20) | 126 (22) | 127 (21) |
| Diastolic blood pressure, mm Hg (SD) | 71 (11) | 71 (11) | 71 (11) |
| At least one copy of the ε4 allele, n (%) | 78 (22) | 106 (35) | 184 (28) |
| Right hemisphere, n (%) | 159 (45) | 126 (42) | 285 (44) |
| Postmortem Interval to Fixation, h (SD) | 9.8 (7.2) | 8.7 (5.9) | 9.3 (6.7) |
| Postmortem Interval to Imaging, d (SD) | 38.5 (20.1) | 39.5 (18.3) | 38.9 (19.2) |
| 3T Siemens Verio | 127 (36) | 102 (34) | 229 (35) |